Decreased energy synthesis can occur in the myocardium during endotoxin shock, and UCP2 may play an important role in this process. The negative correlation between UCP2 expression and energy metabolism requires further study, as the results might contribute to the treatment of sepsis with heart failure.
Acute kidney injury (AKI) during septic shock, which is one of the most common clinical syndromes in the intensive care unit (ICU), has a high mortality rate and poor prognosis, partly because of a poor understanding of the pathogenesis of renal dysfunction during septic shock.
The relationship between respiratory mechanical
parameters and hemodynamic variables remains unclear. This
study was performed to determine whether mean airway pressure
and central venous pressure in the first day of mechanical ventila-
tion are associated with patient outcomes.
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